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This effect is mediated by a reduction in the synthesis of prostaglandins, which are cell-signaling molecules derived from the omega-6 fatty acid arachidonic acid via the action of the cyclooxygenase enzymes (Downie 1991
In sheep models, zinc reduces ROS levels and enhances mitochondrial activity and GSH concentrations, thereby improving oocyte quality and embryonic development during in vitro maturation (IVM) (Yao et al., 2023)
Cell 2015;163:5609
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