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The Phase 3 randomized controlled trial enrolled 2,539 adults with obesity and was published in the New England Journal of Medicine in June 2022 (Jastreboff AM et al, NEJM 2022;387:205-216)
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Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy
J aagric biol sci
Recent regulatory developments include increased FDA enforcement actions against supplements making drug-like claims, FTC scrutiny of weight loss advertising focusing on substantiation of efficacy claims, and concern about supplements marketed as alternatives to prescription medications without adequate evidence
