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Homozygous individuals with this polymorphism (TT genotype) have a 12% prevalence (89)

Therefore, it may be recommendable to assess the level of other trace elements, as cupper or iron, in order to improve micronutrient combination strategies to avoid possible antagonism between them that could decrease their clinical effect

While effective for some, these approaches often fall short for individuals with underlying metabolic challenges, hormonal imbalances, or age-related barriers

However, special care must be used when using lemon juice in the sun as it can cause a reaction on the skin and actually cause or worsen the appearance of existing skin hyperpigmentation