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The precautionary principle applies here: if there's significant cancer risk, other longevity interventions (NAD+ therapy, senolytics, lifestyle optimization) may be safer choices until more human safety data exists

While some online pharmacies may claim to sell retatrutide, the only safe and legal way to get retatrutide today is with a clinical trial

Realistic expectations: Successful candidates understand that AOD-9604 is an adjunct to comprehensive lifestyle modification, not a standalone solution

*Correspondence: Hang Lin, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Tissue Engineering and Regenerative Medicine, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

For now, minoxidil remains the evidence-backed standard