V.ZehtabO.GuigoR.et al (2003)
Medical organizations such as the Cleveland Clinic explain that GLP-1 medications like semaglutide and tirzepatide were originally developed to treat type 2 diabetes before their powerful weight-loss effects were widely recognized
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[26] [27] It's important to note that the SELECT trial , published in 2023, demonstrated cardiovascular benefits with semaglutide 2.4 mg (marketed as Wegovy) in patients without diabetes but with obesity and established cardiovascular disease