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An oral acute toxicity study of GSH in mice found that the lethal dose 50 (LD50) was more than 5 g/kg, indicating that glutathione is nontoxic

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The tryptophan and histidine residues are the photolabile positions, and tryptophan oxidation is the most common degradation route detected by RP-HPLC in stored melanocortin analogues

The pattern repeats across platforms, from Amazon reviews to consumer complaint forums

There is also a well-documented concern about weight regain