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If GLP-1 is in the correct configuration state it will be locked into the active site forming a GLP-1:DPP-IV complex

They provide perks such as greater stability, improved drug protection, and extended drug release

Oxidative stress in tum induces cardiovascular disease, inflammation, and cancer, in addition to extensive skin damage

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Liraglutide (Saxenda), an earlier GLP1 medication, uses a similar approach but has a shorter half-life of about 13 hours, requiring daily injection