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It nudges the body to use stored fat for fuel and limit new fat build up

These changes are often due to decreased endogenous hormone levels

In the central nervous system, GLP-1Rs are located in numerous regions and it is suggested that GLP-1RAs act to promote weight loss through distributed effects rather than a specific or localized response [41]

118 (11.7%) did not complete the trial In adults with established CVD either overweight or obesity, Safety data from the SELECT trial with Wegovy 2.4 mg Safety was evaluated in a trial of 17,604 patients 5 Safety data collection was limited to serious adverse events (including death), adverse events leading to discontinuation, and adverse events of special interest

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