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Semaglutide (also injected weekly) was associated with an average weight loss of around 11% after 24 to 68 weeks, with evidence suggesting the effect can persist for up to two years, based on 18 randomized controlled trials (27 949 participants)

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According to clinical trial data and post-marketing surveillance, these effects are generally dose-dependent (more common with higher doses) and tend to diminish over time as the body adapts to the medication

Wegovy is used for achieving weight management by working alongside a reduced-calorie diet and increased physical activity

These results, presented in 2024, provided the first solid evidence that GLP-1 drugs could meaningfully slow Alzheimers in humans