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A lower dose (750 mg) of LC under fat-mobilizing conditions improved liver fat utilization and ketogenesis without stimulating energy expenditure [40]

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However, liposomal formulations are still temperature-sensitive freezing ruptures the liposomes, and prolonged heat exposure degrades the lipid structure

Three RCTs [13, 33, 34] involving 186 patients provided low certainty evidence (Table 2) that L-carnitine supplementation may induce or no difference in changes in the total cholesterol levels (MD: 11.80, 95%CI: 27.13 to 3.53)