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The available evidence suggests that MSM could be safe for extended use, but this depends on many factors like the dosage and your individual sensitivity
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Am J Respir Crit Care Med 202(7):973982 Wu TD, Brigham EP, Keet CA, Brown TT, Hansel NN, McCormack MC (2019) Association between prediabetes/diabetes and asthma exacerbations in a claims-based obese asthma cohort
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