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For patients focused on body composition (building lean mass while reducing body fat), some providers recommend pairing IGF-1 LR3 with a GLP-1 microdose protocol

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That said, its worth knowing that certain oral GLP-1 medications, like Rybelsus (oral semaglutide), need to be taken on an empty stomach with just a small sip of water, at least 30 minutes before eating or drinking anything else