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The questionnaire screens for conditions that might make semaglutide unsafe, including personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or severe gastrointestinal conditions
Now that millions of people have used the drugs, several obesity experts told The Associated Press that perhaps 20% of patients as many as 1 in 5 may not respond well to the medications
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Consequently, maximum weight loss effects are not observed until patients reach and maintain their target maintenance dose for several months
Originally conceived as a type 2 diabetes therapy rather than a pure obesity drug, DA-1726 was optimized less for maximal appetite suppression and more for metabolic control, which Kim believes may underlie its comparatively better tolerability
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