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Diabetes, Obesity and Metabolism, 24 (8), 1553-1564
The active CASSCF zones included all orbitals (and electrons) that, due to their coupling, transfer significant electron densities from one orbital to another, because of this being located in the so-called HOMO-LUMO zone
AC: Conceptualization, Supervision, Writing original draft, Writing review & editing
Tirzepatide is a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist
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Furthermore, GLP-1 augments mitochondrial efficacy, as manifested by the ameliorated oxidative metabolism of muscle tissue
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