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Published radioligand binding and cAMP accumulation assays report EC50 values comparable to native GLP-1, demonstrating that the modifications affect pharmacokinetics rather than receptor pharmacology
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GLP-1 receptors are expressed in brain regions associated with emotional regulation, including the hippocampus, amygdala, and prefrontal cortex
The needle will be inserted at a 45 degree angle, just below your skin, as opposed to deep in your muscle
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