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In absence of further evidence, lipoic acid supplementation during pregnancy should only be considered under strict medical supervision

Additional research, including studies from our collaborative research groups, has shown that severe reactive astrocytes exhibit the increased production of H 2 O 2 through MAO-B, leading to AD pathology hallmarks such as tauopathy, cognitive decline and neuronal atrophy 57

Gliadin induced release of zonulin by binding to CXCR3 and elevated permeability ex vivo in biopsies of healthy volunteers and patients with quiescent CeD (90, 91)