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[1] In adults with confirmed GH deficiency, sermorelin may also be considered as a treatment option, although its use in healthy older adults for anti-aging purposes remains unproven and is not an FDA-approved indication
Saroglitazar, a dual PPAR / agonist currently used in India for treatment of diabetic dyslipidemia has shown promising effects in experimental models of NASH [64] and seems also to be effective in humans, reducing serum aminotransferase levels and liver size assessed by ultrasound in NASH patients after a 24-week course [65]
The gray-market demand increased after 2023, when the FDA banned compounding pharmacies from producing many of these peptides due to safety concerns, including the risk that peptides may clump together and cause the immune system to react in unpredictable ways
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