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Measurements using body composition methods (DEXA, bioimpedance, caliper) are more informative than scale weight alone, as AOD-9604 may preserve lean tissue while selectively reducing fat mass

Useful experimental controls may include vehicle-treated controls, positive controls for migration or angiogenesis, pathway inhibitors for NO or FAK-related signaling, and analytical confirmation of peptide identity and purity

However, tendons are also susceptible to injury and can often be slow to heal

These new findings further support to the use of B 12 supplementation especially in terms of delivering the vitamin to astrocytes within the brain while revealing that fingolimod can correct the impaired astrocyte-B12 pathway in people with MS