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It scavenges free radicals, mitigates oxidative stress, and suppresses pro-inflammatory mediators like TNF- , IL-6, and COX-2 by inhibiting the NF-B signaling pathway (11, 12, 26, 27)
The primary routes for permeation across the BBBinclude passive diffusion (lipid soluble solutes), ABC transporter efflux, carrier-mediated influx, and receptor-mediated transcytosis (Pandian et al., 2022
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We next examined whether GSTM2 interacts with ASK1 by conducting a co-immunoprecipitation assay
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