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Peripheral neuropathy may take 36 months to improve, and some patients experience incomplete recovery, particularly if treatment was delayed
Also investigated for cartilage repair and bone regeneration
Mechanism of Action Through careful experimentation, cellular fat accumulation has been associated with increased activity of nicotinamide N-methyltransferase (NNMT)
Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials
Use them at different times or on alternating days
