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Taken together, the paper effectively captured the fields enthusiasm, framing GLP-1 therapies as uniquely positioned to act across the full pathological spectrum of Alzheimers disease rather than targeting a single downstream lesion
[8] [9] Bupropion (Zyban) is licensed in the UK specifically as an aid to smoking cessation, not for depression, and works on dopamine and noradrenaline pathways
Acta Pharmacol Toxicol 59(Suppl 7):450453 James SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, Neubrander JA (2004) Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism
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Yes, rapid weight loss can alter hormone levels and metabolism, potentially leading to mood swings and irritability
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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