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The cyanide group in its structure sets cyanocobalamin apart from other B12 types
Schedule: TB-500 twice weekly (loading) then once weekly (maintenance)
the standard BNF loading regimen is 1 mg on alternate days for two weeks, followed by 1 mg every three months for maintenance
Unlike shots, nasal delivery causes no pain, soreness, or injection site reactions
In March 2011, the FDA placed the trial on clinical hold due to GMP compliance issues at the contract manufacturer not safety concerns with RGN-352 itself
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