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Opposite results were also found in isolated adult rat cardiomyocytes that contraction was not be accelerated after treated with GLP-1 (107), accompanied with a decreased left ventricular contractility (108)

A 7-fold increase in bioavailability means that a 500 mcg oral dose of the arginate form could deliver the equivalent systemic exposure of approximately 3,500 mcg of the acetate form taken orally

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thus, clinicians should withhold Bi-Amino Injection until arterial pH is stabilised above 7.30 to prevent compounded acid-base derangement