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This evidence, combined with earlier trials on people with type 2 diabetes, led the FDA to extend the indications for Wegovy
6,10 At baseline, 97% were treated with one or more glucose-lowering medications: metformin (76%), insulin (51%), SGLT-2 inhibitor (27%), sulfonylurea (29%), and DPP-4 inhibitors (23%)
Exenatide treatment was associated with a prolonged increase of phosphorylation of insulin receptor signaling substrate-1 (IRS1) phosphorylated at tyrosine residues at 24, 48, and 60 weeks
10.1016/j.metabol.2017.09.013 56 Garca RubioM
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