glp-1 research papers Exploration of the potential association between receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database | BMC Medicine Current Insights, Advantages and Challenges

FIGURE 1 2.2 Search strategy A systematic search of scientific literature was conducted in the Web of Science (Core Collection), Scopus, and PubMed databases, including studies published up to November 2025 without country restrictions

GLP-1 injections mimic a natural hormone that regulates appetite, slows digestion, and helps control blood sugar levels

The use of GLP-1R agonists was associated with fewer intra-articular injections of steroids and a lower cartilage loss velocity from the medial femoral joint, but the direct effects of GLP-1R agonist, apart from the weight loss-mediated pathway, did not reach statistical significance

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AWARD-11: dulaglutide 3.0 and 4.5 mg for the treatment of type 2 diabetes