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While taste changes during treatment with GLP-1 receptor agonists or dual GIP/GLP-1 receptor agonists are generally benign and self-limiting, certain situations warrant medical evaluation to rule out complications or alternative diagnoses

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GIP receptor signaling GIP is secreted by intestinal K cells after nutrient ingestion and, like GLP-1, stimulates glucose-dependent insulin secretion

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That is exactly what the most promising peptide research aims to achieve