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Nevertheless, LC is able to prevent lipid peroxidation by its antioxidant properties [28], which is in accordance with the results of the present investigation

Compared to wild-type BoNT/X protease, both X(PC2)b, an earlier evolutionary intermediate with activity on both VAMP1 and procaspase-1, and X(PC) demonstrated more stringent substrate requirements (Fig

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Within the structure, TT-OAD2 protrudes beyond the receptor core to interact with the lipid or detergent, providing an explanation for the distinct activation kinetics that may contribute to the clinical efficacy of this compound series

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