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The development of further dual GLP-1/GIP receptor agonists seems to be a promising next step in managing various cardiovascular disease

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The combined activation of GIPR and GLP-1R by tirzepatide not only improved both glucose-dependent insulin secretion and glucose tolerance in mice 38 , but also showed significantly better efficacy than semaglutide and dulaglutide with regard to glucose control and weight loss 15,16