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Here is what the data and user reports tell us

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Consistent with this, we demonstrate that treatment with MK-801, even at doses that do not evoke weight loss, elicits pronounced hyperthermia in DIO mice (Extended Data Fig

There's no doubt that Roche is playing catchup in the category, one of a lengthening list of pharma companies that are hoping to hit on effective 'me-too' products that can make a dent in the substantial lead held by market leaders Novo Nordisk and Eli Lilly, which already have injectable GLP-1s for diabetes and obesity on the market