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Lower blood pressure and BW loss correlate independently with SGLT2 inhibitor treatment, with the effect of both GLP-1RA and SGLT2 inhibitors being significantly greater on systolic BP than on diastolic BP [4]
If any of these occur, step back up one dose level and stabilize for four to eight weeks before attempting the reduction again
These associations with non-invasive biomarkers such as ELF have not been established
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