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They are grouped together because they target the same aspects of aging, not because they share a structure
Tumor cells promote an angiogenic switch in endothelial cells by secreting pro-angiogenic factors such as VEGF, platelet-derived growth factor (PDGF), and angiopoietin 2 (Ang-2), inducing the destabilization of the endothelial cell barrier and promoting endothelial cell migration and proliferation (22)
Methylation levels of NLRP3, TGF1, MCP-1, and TNFSF2 are significantly lower in DR patients compared to healthy individuals, suggesting that hypomethylation of these genes contributes to DR progression [66]
The outcome produced a safe and effective route of administration without adverse effects
Aging 12 , 336338 (1991)
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