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The disease is triggered by a series of factors, with associated causative factors, e.g., obesity, age, trauma, sex, and ethnicity [2, 3]

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Taken as a once-weekly injection, tirzepatide is often chosen by women who want a stronger effect on appetite, or who have plateaued on another GLP-1

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For instance, although early life stress induces an attenuated CRH expression in the PVN, plasma corticosterone remains elevated ( Most studies of early life stress focus on corticosterone as the major output of the HPA-mediated stress-response