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Other contributing factors include medication interactions (certain psychiatric medications, corticosteroids, and reduced exposure to oral contraceptives during dose escalation), hormonal changes (thyroid dysfunction, menopause), inadequate sleep (less than 7 hours nightly), chronic stress with elevated cortisol, and reduced physical activity as patients become more comfortable at their current weight
The article asks patients to be transparent about fatigue, temperature sensitivity and mood changes during semaglutide therapy
other, 31 (10.8 percent)
However, both cohorts would be affected similarly by this process
However, weight loss itself can affect hormones (PCOS symptoms often improve with fat loss, for example), and individual responses vary
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