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Adequate hydration is critical, as insufficient fluid intake can lead to oesophageal or intestinal obstruction, particularly in individuals with swallowing difficulties or pre-existing gastrointestinal strictures

To address this critical knowledge gap, we leveraged a large, population-based whole-exome sequencing dataset from the UK Biobank to systematically investigate the association between high-confidence protein-truncating variants (PTVs) and PD risk

This is where the strategy lives or dies for most people

Overdosing is a risk

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