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Furthermore, 58 M Cu(OAc) 2 also upregulated the IL-1 expression significantly

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However, their activity decreases with aging, creating an imbalance between oxidative damage and repair mechanisms.12 Excessive accumulation of reactive oxygen species (ROS) within hair follicle melanocytes leads to cellular damage through lipid peroxidation, DNA strand breaks, mutations, and protein and enzyme denaturation

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