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Unlike generalized limb disuse, this unloading occurs in a mechanically altered and inflammatory microenvironment characterized by tendon retraction, impaired force transmission, and local hypoperfusion
Animal data shows combined effects on tendon/ligament healing (faster collagen, less inflammation) and wound repair
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RCM features nondilated ventricles with impaired diastolic function, causing wall stiffening and restricted filling (29)
