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As GLP-1 binds to GLP-1 receptors expressed on pancreatic cells, the receptors couple to G-protein subunits and activate adenylate cyclase, which increases the production of cAMP from ATP

Reverse Transcription quantitative Polymerase Chain Reaction (RT-qPCR) PA-TU-8902 cells were incubated for 24 h before treatment

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Steatosis is defined histologically extensive cytoplasmic vacuolization, whereas ballooning is a type of hepatocyte degeneration with marked swelling and enlargement of individual hepatocytes 56