BMJ Case Reports, bcr-2017-221854
Beyond gastrointestinal symptoms, other documented adverse effects include injection site reactions, fatigue, headache, and dizziness
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Skin shows early-to-moderate signs of photoaging: fine lines around the eyes and mouth, mild laxity, occasional loss of plumpness, possibly the beginnings of static rhytids
Furthermore, genetic studies have identified regulators such as DJ-1 as important modulators of microglial resilience, paving the possibility for medicines that improve endogenous anti-inflammatory pathways rather than widely reducing immune activity [183]