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Some of the primary benefits of methylation include: DNA synthesis and repair Gene expression Neurotransmitter synthesis Hormone regulation Detoxification Immune system function Energy production Toxins and Their Impact on Methylation, Glutathione, and Antioxidant Production Toxins, including environmental pollutants, drugs, and chemicals in food, can impair the methylation pathway by interfering with the enzymes involved in the process
Many vitamins and plant-based compounds are antioxidants
High ROS in SNpc neurons usually results from dopamine metabolism, low glutathione, and high levels of iron and calcium 20
Integrative pharmacology reveals the mechanisms of Erzhi pills, a traditional Chinese formulation, stimulating melanogenesis
However, it is still controversial
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