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Cautionary Statement Regarding Forward-Looking Statements This press release contains forward-looking statements (as that term is defined in the Private Securities Litigation Reform Act of 1995) about Zepbound (tirzepatide) as a treatment for adults with obesity, or overweight with at least one comorbidity, who do not have diabetes and reflects Lilly's current beliefs and expectations

For best outcomes, most patients undergo 48 sessions, spaced weekly or bi-weekly

Same rules, same temperatures, same emphasis on minimizing exposure

Supplemental Figs

Semaglutide begins to reduce appetite within the first week, with the most significant effects typically occurring after 2-4 weeks of treatment