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Earlier work in Planta Medica by Liu and colleagues demonstrated that madecassoside increases collagen synthesis and reduces inflammatory infiltration in vivo [16]

While the evidence is not as strong as for PPIs, probiotics carry essentially zero risk and may help with multiple GI symptoms simultaneously, including the bloating that often accompanies heartburn

Many, and widespread, it turns out

As of the time of writing, both agents remain in clinical development and have not received a marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA)

Exosomes derived from mesenchymal stem cells attenuate NLRP3-related pyroptosis in autoimmune premature ovarian insufficiency via the NF-B pathway