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7A, B) 46,47,48
Thus, integration of both hormones into a single molecule may not only maximize the metabolic efficacy of the individual signals, but allow also specific delivery of estrogen into GLP1 receptor-expressing cells, avoiding potential undesired effects of estrogen on reproductive tissues, as shown also in our studies
NEJM evidence
But anytime a drug goes from niche diabetes treatment to cultural phenomenon in the span of a couple years, its worth stepping back and asking: how safe are these, really
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