PMID 32886826
The peptide stability guide compares shelf life and degradation profiles across commonly used peptides
Immunoblot of LRP8 in 786-O cells transduced with a sgControl or sg LRP8
Chemical properties Chemical Name: L--glutamyl-L-cysteinyl-glycine Molecular Formula: C10H17N3O6S CAS: 70-18-8 (reduced form) Molecular Weight: 307.32 g/mol Biological Significance Antioxidant Protection In our daily lives, the body constantly produces reactive oxygen species (ROS) and free radicals, which attack cell membranes, proteins, and DNA, causing oxidative stress, accelerating aging, or triggering diseases
GHK-Cu is predominantly found in saliva, blood, and urine, and has multiple biological actions when administered to test subjects, including [1]: Antioxidant gene activity [2] Suppression of inflammatory cytokine interleukin-6 [2] Increased protein accumulation [3] Increased collagen synthesis [3] In animal models, GHK-Cu has been shown to increase an anti-inflammatory proteogly called decorin that can protect diabetic rats from kidney-damaging fibrosis [2, 4]