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Excessive enhancement of ER-mitochondria calcium coupling may increase susceptibility to permeability transition, whereas excessive attenuation can impair antimicrobial signaling and lymphocyte activation, indicating that efficacy and clinical acceptability are likely to depend on cell type, disease stage and dosing regimen (162)
Chiara K
Wegovy pens are single-dose only and should be discarded after use in an FDA-cleared sharps container
Jan 2021;25(1):438-446
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