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The peptides effects on enteric neurons, glial cells, and gut barrier integrity suggest multiple pathways through which healing the gut could protect the brain
Muscle and lean mass Some of the weight lost on any GLP-1 medication is muscle, not fat
Key findings from clinical trials include: Reductions in waist circumference, an indirect marker of abdominal fat Improvements in metabolic markers associated with visceral adiposity (HbA1c, lipid profiles, liver enzymes) Decreased hepatic fat content in patients with fatty liver disease It is important to understand that GLP-1 medications do not 'burn' fat through thermogenesis or direct lipolysis
Progesterone and estrogen regulate oxidative metabolism in brain mitochondria
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