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Cancer / proliferation concern: Potentiating c-Met (a proto-oncogene product) raises a legitimate theoretical risk of promoting pre-existing or nascent malignancy
Key Takeaways GLP-1 medications are associated with a higher risk of gallstones and gallbladder disease, and FDA labeling for Zepbound and Wegovy lists gallstones and acute cholecystitis as possible risks
In February, based on early results of promising anti-tumor activity and manageable safety profile from a Phase I study, the FDA granted Fast Track Designation to CUSP06, a Cadherin-6 ADC employing exatecan as the payload, for the treatment of PROC
She's reallly good with face fat transfer and cheek fat removal
Gut microbiome modulation : Early research suggests that GLP-1 receptor agonists like semaglutide may influence gut microbiota composition, though the clinical significance remains unclear and evidence is limited
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