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Choice of treatment(s) dependent on individual clinical factors and preference Untreated hyperthyroidism Hyperthyroidism Hypersecretion of thyroid hormones from the thyroid gland

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The literature is a mixture of foundational biochemistry, preclinical models, small clinical or cosmetic studies, and a large volume of anecdote

Moreover, interventions that broadly suppress microglial activity risk impairing their essential physiological functions, including synaptic pruning, neurogenesis regulation, and clearance of cellular debris [490492]

We also flag recurring hurdles: imbalanced data, the difficulty of annotating posts (especially when drug-event links are implied rather than explicit), few papers with clear annotation guidelines, heavy reliance on shared-task datasets like Social Media Mining for Health (SMM4H), and a strong bias toward English with limited work in languages such as French or Chinese