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The mechanistic insight that dataset can firmly support remains, at present, narrower than its breadth implies

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Due to its targeted interaction with NNMT, 5-Amino-1MQ serves as a valuable research tool for studying metabolic enzyme activity and peptide-independent regulatory mechanisms

We and others have shown that circulating leptin levels are reduced in chronic stress animal models of depression [15,16,17], whereas systemic and intracerebroventricular injections of leptin produce antidepressant-like behavioral effects [15, 18,19,20]

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