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It names HPLC with UV detection and mass spectrometry as the methods

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Indeed, benzoquinones can covalently react with diverse macromolecules whereas hydroquinones, conjugated or not with glutathione, are prone to auto-oxidation forming reactive oxygen species

Despite advances in chemotherapy, radiotherapy, and targeted therapies, challenges such as poor drug accumulation, systemic toxicity, and multidrug resistance persist, partly due to elevated intracellular GSH levels that neutralize reactive therapeutics and reduce treatment response

Melatonin is a circadian hormone that primarily times the sleep-wake rhythm