A change in clarity is generally the most reliable early sign, since a properly reconstituted and well-stored solution should remain visually consistent throughout its usable life
Nat Rev Dis Primers 2 , 16082 (2016)
It previously held FDA approval (marketed as Geref) for diagnostic testing of GH deficiency and as a treatment for pediatric growth-hormone deficiency, providing a substantial base of human pharmacokinetic and safety data that continues to inform current research into pulsatile GH secretion, sleep-related GH release, and recovery physiology
Avoid injecting into areas that are bruised, tender, red, or hard
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